KEGG   Bos taurus (cow): 525072
Entry
525072            CDS       T01008                                 
Symbol
PLA2G4A
Name
(RefSeq) cytosolic phospholipase A2
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
bta  Bos taurus (cow)
Pathway
bta00564  Glycerophospholipid metabolism
bta00565  Ether lipid metabolism
bta00590  Arachidonic acid metabolism
bta00591  Linoleic acid metabolism
bta00592  alpha-Linolenic acid metabolism
bta01100  Metabolic pathways
bta04010  MAPK signaling pathway
bta04014  Ras signaling pathway
bta04072  Phospholipase D signaling pathway
bta04217  Necroptosis
bta04270  Vascular smooth muscle contraction
bta04370  VEGF signaling pathway
bta04611  Platelet activation
bta04664  Fc epsilon RI signaling pathway
bta04666  Fc gamma R-mediated phagocytosis
bta04724  Glutamatergic synapse
bta04726  Serotonergic synapse
bta04730  Long-term depression
bta04750  Inflammatory mediator regulation of TRP channels
bta04912  GnRH signaling pathway
bta04913  Ovarian steroidogenesis
bta04921  Oxytocin signaling pathway
bta05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    525072 (PLA2G4A)
   00565 Ether lipid metabolism
    525072 (PLA2G4A)
   00590 Arachidonic acid metabolism
    525072 (PLA2G4A)
   00591 Linoleic acid metabolism
    525072 (PLA2G4A)
   00592 alpha-Linolenic acid metabolism
    525072 (PLA2G4A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    525072 (PLA2G4A)
   04014 Ras signaling pathway
    525072 (PLA2G4A)
   04370 VEGF signaling pathway
    525072 (PLA2G4A)
   04072 Phospholipase D signaling pathway
    525072 (PLA2G4A)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    525072 (PLA2G4A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    525072 (PLA2G4A)
   04664 Fc epsilon RI signaling pathway
    525072 (PLA2G4A)
   04666 Fc gamma R-mediated phagocytosis
    525072 (PLA2G4A)
  09152 Endocrine system
   04912 GnRH signaling pathway
    525072 (PLA2G4A)
   04913 Ovarian steroidogenesis
    525072 (PLA2G4A)
   04921 Oxytocin signaling pathway
    525072 (PLA2G4A)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    525072 (PLA2G4A)
  09156 Nervous system
   04724 Glutamatergic synapse
    525072 (PLA2G4A)
   04726 Serotonergic synapse
    525072 (PLA2G4A)
   04730 Long-term depression
    525072 (PLA2G4A)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    525072 (PLA2G4A)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    525072 (PLA2G4A)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     525072 (PLA2G4A)
SSDB
Motif
Pfam: PLA2_B C2 cPLA2_C2
Other DBs
NCBI-GeneID: 525072
NCBI-ProteinID: NP_001069332
BGD-bta: BT16529
Ensembl: ENSBTAG00000013298
VGNC: 32960
UniProt: A4IFJ5
Position
16:67907024..68081280
AA seq 749 aa
MSFIDPYQHIIVEHHYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISSTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENILEITLMDANYVMDETLGTTTFPISSMKVGEKKQV
PFIFNQVTEMILEMSLEVCSSPDLRFSMALCDQEKAFRQQRKENIKENMKKLLGPKNSEG
LHSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSH
PDFPEKGPEEINKELMKNVSHNPLLLLTPQKIKRYVESLWRKKSSGQPVTFTDIFGMLIG
ETLIHNRMNTTLSSLKEKVNTGQCPLPLFTCLHVKPDVSELMFADWVEFSPFEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSKGSTMEEE
LENITAKHIVSNDSSDSDDESQGPKGTEHEEAEREYQNDNQASWVQRMLMALVSDSALFN
TREGRAGKVHNFMLGLNLNTSYPMSPLRDFTMQESLDEDELDAAVADPDEFEQIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPGDSSPPFKELLLAEKWAKMN
KLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETN
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIVESIEYRR
QNPSRCSVSLSSVEARRFFNKEFLSKPTA
NT seq 2250 nt   +upstreamnt  +downstreamnt
atgtcatttatagatccttatcaacacattatagtggagcaccattattcccacaagttc
acagtagtggtgctgcgtgccacaaaagtgacaaagggaacctttggtgacatgcttgac
actccagacccctatgtggaacttttcatctcttcaacccccgacagcaggaagagaaca
agacacttcaataatgacataaaccctgtgtggaatgagacctttgaatttattttggat
cctaatcaggaaaatattttggagatcactttaatggatgccaattatgttatggatgaa
actcttgggacgacaacgtttcccatatcttctatgaaagtgggagagaagaaacaggtt
ccttttattttcaatcaagtcactgaaatgattctggaaatgtctcttgaagtttgttca
tccccagacctccggtttagtatggctctgtgtgaccaggagaaagctttcagacaacag
agaaaggaaaacataaaggaaaacatgaagaaactgctgggtccaaagaatagtgaaggc
ttgcattctacacgtgatgtgcctgtggtggccatactgggctcaggtgggggatttcga
gccatggtaggattctctggtgtgatgaaggcactgtatgagtcagggattttggactgt
gctacctacattgctggtctttctggatccacatggtatatgtcgaccttatattctcac
cctgattttccagagaaagggccagaggagattaacaaagagctaatgaaaaatgtcagc
cacaaccctcttttacttctcacaccacagaaaattaaaagatatgttgagtctttatgg
aggaaaaaaagttctggacaacctgtcacctttactgatatcttcgggatgttaatagga
gaaacactaattcacaatagaatgaacactaccctgagtagtttgaaggaaaaagtcaat
actgggcagtgtcctctgccgcttttcacctgtctccatgtcaaacccgatgtctcagag
ctgatgtttgcagattgggttgaatttagtccatttgagattggcatggctaaatatggt
acttttatggcgcctgacttatttggaagcaaattttttatgggaacagttgtaaagaaa
tacgaagaaaaccccttgcatttcttaatgggtgtctggggtagtgccttttctatattg
ttcaacagagtcttgggagtttctggatcacaaagtaaaggttccacaatggaagaagaa
ctagaaaatattacagcaaagcatattgtgagtaatgatagctcagacagtgatgacgaa
tcacaaggacccaaaggcactgaacatgaagaagcagaaagggaataccaaaatgataat
caagcaagttgggtccaacgtatgctcatggccttggtgagtgactcagctttgttcaat
accagagaaggacgtgccgggaaggtgcacaacttcatgctgggcttgaatctcaataca
tcctatccaatgtctcctttgagagactttaccatgcaagagtccctggatgaagacgaa
ttggatgccgctgtcgcagatcctgatgaatttgagcagatatatgagcctttggatgtc
aaaagtaaaaagattcatgtggtggacagtggcctcacatttaaccttccataccctttg
atcctgagacctcagaggggagttgatctcatcatctcctttgacttttctgcaagacca
ggtgactccagtcctccgttcaaggaacttctacttgcagaaaagtgggctaaaatgaac
aagctcccctttccaaagattgatccttacgtattcgatcgagaaggactgaaggaatgc
tatgtttttaaacccaagaatcctgatgtcgagaaagattgcccgactatcattcacttt
gttctggccaacatcaacttcagaaagtacaaggctccaggtgttccaagagaaactaat
gaagagaaagaaatagctgattttgatatttttgatgaccctgaatcaccgttttcgacc
ttcaactttcaatatcccaatcaagcatttaaaaggctgcatgatctcatgtacttcaat
accctgaacaacattgatgtaataaagaatgctatagtcgaaagcatcgaatatagaagg
cagaatccgtctcgttgctctgtttccctcagtagtgttgaggcaagaagattcttcaac
aaggagtttctaagcaaacccacagcatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (71)   

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